Differential susceptibility to bronchial carcinogenesis in syngeneic hamsters.

Differential Susceptibility to Bronchial Carcinogenesis in Syngeneic Hamsters1

Previous studies of chemical carcinogenesis in the lung of Syrian golden hamsters have utilized outbred (nonsyngeneic) animals. Using the endobronchial sustained release implant technique, which causes focally orig inating cancers in outbred hamsters, we studied the course of bronchial carcinogenesis in two varieties of syngeneic Syrian golden hamsters, the I SI I and the 1,1) strains (BIO 15.1...

Bronchial and pulmonary carcinogenesis at focal sites in dogs and hamsters.

Models of the sequential process of lung carcinomas have been developed in dogs and hamsters. The bronchial mucosa, or the pulmonary parenchyma, was exposed at selected focal sites to polycyclic aromatic hydrocarbons [most often benzo(a)pyrene or methylcholanthrene]. In hamsters, sustained release implants that contained carcinogen were implanted into the right lower lobe bronchus. In dogs, for...

Spectrum of tumorigenic phenotypes among adenovirus 2-, adenovirus 12-, and simian virus 40-transformed Syrian hamster cells defined by host cellular immune-tumor cell interactions.

The tumor-inducing capacities of adenovirus type 2-, adenovirus type 12-, and SV40-transformed LSH hamster embryo cell define a spectrum of four distinct tumorigenic phenotypes: type I, nononcogenic for newborn hamsters but oncogenic for nude mice; type II, oncogenic for newborn hamsters but nononcogenic in syngeneic adults; type III, oncogenic for both newborns and syngeneic adults; and type I...

Genetic Polymorphisms of Glutathione S-Transferase mu1 (GSTM1) and Theta1(GSTT1) and Bronchial Asthma Susceptibility in Ukrainian Population

Effect of laser irradiation on the progression of skin cancer using carcinogen among hamsters

Introduction: Skin cancer has been increased day by day, but it can be cured if it diagnosed early. After reviewing the scientific literature about 980 nm diode laser, and its multiple advantages on skin diseases. We studied in this paper the effectiveness of this type of laser on the progression of skin cancer among hamsters which were exposed to carcinogen on the bac...